Pain
Conditions
Interventions
group A:Group A was given 0.15g of dextroibuprofen capsules orally for the first time. If the pain did not significantly relieve within 30 minutes after taking the drug (NRS>=3), 0.15g was added. Obse
group B:Group B was given 0.3g of dextroibuprofen capsules orally for the first time. If there is no significant relief of pain within 30 minutes after taking the drug (NRS>=3), add 0.3g
Observation was continued for 30min, and if no relief was achieved, 0.3g was taken again, and so on, until the NRS score dropped below 3 points or adverse drug reactions occurred
Sponsors
Sanbo Brain Hospital, Capital Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Outpatient patients with acute or chronic pain, Pain rating (NRS) >=3; 2. 18-75 years old (including 18 and 75 years old), both male and female; 3. Subjects voluntarily agree to participate in the study and sign a written informed consent
Exclusion criteria
Exclusion criteria: 1. Participated in clinical research of other drugs within 1 month; 2. People who have been known to be allergic to NSAIDS or can induce symptoms such as asthma and urticaria after taking NSAIDS; 3. Patients with previous active digestive ulcer, bleeding or perforation, Crohn's disease, hemorrhagic disease, and severe cardiac, liver, and renal insufficiency; 4. Previous mental and nervous system diseases or suspected dementia or memory impairment; 5. Patients with auditory, visual, and language system function impairment who cannot complete the assessment; 6. Pregnant and lactating women or women of childbearing age who are trying to conceive; 7. Patients and their families rejected the study; 8. Other situations in which the researcher considers it inappropriate to participate in this experiment
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Numerical rating scale;Cumulative dosage;Duration of efficacy; | — |
Secondary
| Measure | Time frame |
|---|---|
| Adverse drug reaction; | — |
Countries
China
Contacts
Public ContactWang Baoguo
Sanbo Brain Hospital, Capital Medical University
Outcome results
None listed