Abdominoplasty
Conditions
Interventions
Intervention group (L group):Administering the low-opioid anesthesia to patients: Intravenous pump dexmedetomidine 0.5ug/kg, after 10 minutes of pumping, Anesthesia was induced by intravenous injectio
Control group(C group):Control anesthesia will be induced by intravenous injection of midazolam 2mg, dexamethasone 0.1mg/kg, propofol 1.5-2.5 mg/kg, sufentanil 0.4ug/kg and vecuronium 0.1mg/kg. Propof
Sponsors
Yan 'an Hospital of Kunming City
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1.Having signed an informed consent; 2.ASA class I-III;3.Aged 18-70 years old;4. Undergoing a scheduled abdominoplasty .
Exclusion criteria
Exclusion criteria: 1.Individuals who are allergic to dexmedetomidine or esketamine; 2.Patients with II-III° atrioventricular block and sinus bradycardia (preoperative HR 180 mmHg and/or DBP > 100 mmHg when calm down); 9.Individuals already participating in other studies.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary outcome is the quality of postoperative recovery according to the QoR-15 questionnaire scores on postoperative day 2(POD2);The primary outcome is the quality of postoperative recovery according to the QoR-15 questionnaire scores on postoperative day 1(POD1); | — |
Secondary
| Measure | Time frame |
|---|---|
| The primary outcome is the quality of postoperative recovery according to the QoR-15 questionnaire scores on postoperative day 3(POD3);the time to first flatus,and first time get out of bed;NRS scale;Extubation time;Intraoperative and postoperative opioid consumption (morphine equivalent);The anxiety and depression status of patients;Length of hospital stay;The incidence of postoperative nausea and vomiting (PONV);The concentration of IL-6 and CRP was performed preoperatively and postoperatively; | — |
Countries
China
Contacts
Public ContactGao Qilian
Yan 'an Hospital of Kunming City
Outcome results
None listed