Cognitive impairment after stroke can result in impaired cognitive functions such as memory, attention, execution, comprehension, and judgment, seriously affecting the patient's daily life and social activities, and hindering comprehensive recovery after stroke
Conditions
Interventions
Test group:Conventional rehabilitation therapy+Transcutaneous vagus nerve electrical stimulation (ear nail area)
Control group:Conventional rehabilitation therapy+Transcutaneous vagus nerve electrical stimulation (in the ear area)
Sponsors
Yuebei People’s Hospital
Eligibility
Sex/Gender
All
Age
40 Years to 85 Years
Inclusion criteria
Inclusion criteria: 1.Patients confirmed by CT or MRI as having a stroke; 2.Meets the diagnostic criteria for PSCIND, with MoCA score<26 and MMSE score = 21; 3.Stable condition, able to cooperate in completing fNIRS testing; 4.First onset, course of illness between 2 weeks and 6 months; 5.Individuals aged 40-85; 6.Having received at least 6 years of education; 7.Not receiving non-invasive neuromodulation therapy for the brain in the past 3 months;
Exclusion criteria
Exclusion criteria: 1.Individuals with consciousness disorders, severe visual, hearing, and language impairments, as well as other health assessments that cannot be completed; 2.There are other types of brain diseases (multiple sclerosis, brain tumors, etc.); 3.Cognitive impairment caused by other reasons, such as Alzheimer's disease (AD), Lewy body dementia, etc; 4.Patients after intracranial implantation of metal, electronic devices, and metal skull repair surgery; 5.Patients with contraindications to vagus nerve electrical stimulation (such as atrial fibrillation); 6.Patients who have had their ears removed, causing the stimulation device to be unable to be placed; 7.Combining tumors, severe systemic diseases such as heart and lung diseases; 8.Pregnant, breastfeeding, or planning to conceive; 9.Due to other reasons, the subjects were unable to tolerate the test during the trial process; 10.Patients and their families who are unwilling to sign informed consent forms;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| fNIRS;MoCA; | — |
Secondary
| Measure | Time frame |
|---|---|
| MMSE;MBI; | — |
Countries
China
Contacts
Public ContactLiu Tingting
Yuebei People’s Hospital
Outcome results
None listed