Pelvic organ prolapse (POP) refers to a disease in which the pelvic organ is detached from the vagina due to weak supporting tissue, resulting in functional abnormalities. Structural defects of the vagina and its supporting tissue are thought to be related to the development of POP. The anterior wall of the vagina is the most commonly affected site of POP. Prolapse of anterior vaginal wall (AVWP)
Conditions
Interventions
AVWP:None
Sponsors
The Third Affiliated Hospital of Guangzhou Medical University
Eligibility
Sex/Gender
Female
Age
40 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Females aged between 40 and 70 years; 2. Patients with total hysterectomy in our center;
Exclusion criteria
Exclusion criteria: 1.Patients with autoimmune or connective tissue diseases; 2.Patients with a history of malignant tumors; 3.Patients with a history of pelvic and vaginal surgery.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Changes in collagen metabolism, autophagy and castor1/mtor signaling pathways; | — |
Countries
China
Contacts
Public ContactJuan Liu
The Third Affiliated Hospital of Guangzhou Medical University
Outcome results
None listed