Frailty
Conditions
Interventions
test team:Intramuscular injection of vitamin D2 600,000 units/time, 2 per month,Health education
control group:Health education
Sponsors
The First Affiliated Hospital of the Air Force Medical University
Eligibility
Sex/Gender
All
Age
60 Years to No maximum
Inclusion criteria
Inclusion criteria: (1) Age >= 60 years; (2) With the ability to act independently and be able to cooperate with the examination and medication; (3) Agree to participate in this study and sign the informed consent form.
Exclusion criteria
Exclusion criteria: (1) Patients with hypercalcemia, urinary calculi or parathyroid diseases; (2) taking vitamin D preparation orally for 3 months; (3) Have a history of vitamin D allergy; (4) Hepatic and renal insufficiency; (5) Patients with severe infection or advanced tumor; (6) serious disability and loss of wisdom; (7) People with cognitive dysfunction.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 25(OH)D;Fried Inventory; | — |
Secondary
| Measure | Time frame |
|---|---|
| Lymphocyte subsets;IL-1ß;IL-6;IL-10;TNF-a;Ca2+;PTH; | — |
Countries
China
Contacts
Public ContactXiaoming Wang
The First Affiliated Hospital of the Air Force Medical University(Xijing Hospital)
Outcome results
None listed