Aplastic anemia
Conditions
Interventions
MUD-cord group:None
Matched sibling donor (MSD) group:None
Haploidentical (Haplo) transplantation group:None
Sponsors
Zhejiang Provincial Hospital of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: (1) meet the diagnostic criteria of severe aplastic anemia and transfusion-dependent non-severe aplastic anemia; (2) voluntary choice of hematopoietic stem cell transplantation; (3) no severe organ dysfunction or active infection.
Exclusion criteria
Exclusion criteria: (1) with congenital bone marrow failure, including fanconi anemia (FA), dyskeratosis congenita (DKC), and diamond-blackfan anemia (DBA). (2) with other or secondary pancytopenia such as paroxysmal nocturnal hemoglobinuria (PNH), myelodysplastic syndrome (MDS), and hairy cell leukaemia (HCL). (3) incomplete follow-up information.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The overall response rate (ORR);The 2-year overall survival;; | — |
Secondary
| Measure | Time frame |
|---|---|
| The 2-year event-free survival;Mixed chimerism rate; | — |
Countries
China
Contacts
Public ContactWu Dijiong
Zhejiang Provincial Hospital of Traditional Chinese Medicine
Outcome results
None listed