Calcific aortic valve disease
Conditions
Interventions
Calcific aortic valve disease grope:None
No calcific aortic valve disease group:None
Sponsors
The First Medical Center of the Chinese PLA General Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 100 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: 1) age >18 years; 2) It plans to undergo surgical aortic valve replacement, Bentall operation and heart transplantation;
Exclusion criteria
Exclusion criteria: Exclusion criteria: 1) history of previous aortic root surgery, resulting in structural changes of aortic valve; 2) Combined with syphilitic heart disease, aortic sinus aneurysm and other diseases that lead to abnormal aortic valve structure; 3) Combined with Marfan syndrome, Takayasu arteritis and other connective tissue diseases that can affect the aortic valve structure; 4) Special groups: children, pregnant or lactating women, patients with mental disorders; 5) The investigator judged that the patients were not suitable for enrollment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Proteins expression levels of aortic valve tissue ;RNA transcription levels of aortic valve tissue;Aortic valve calcification volume; | — |
Countries
China
Contacts
Public ContactChen Yundai
Chinese PLA General Hospital
Outcome results
None listed