Obstructive sleep apnea hypopnea syndrome(OSAHS)
Conditions
Interventions
Normal control group:None (Test: sleep fiber laryngoscope, upper airway CT, airway manometry)
Case group:None (Test: sleep fiber laryngoscope, upper airway CT, airway manometry)
Sponsors
The Second Affiliated Hospital of Zhejiang University School of Medicine
Eligibility
Sex/Gender
Male
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: (1) Patients with typical clinical symptoms of OSA, polysomnography showed an AHI of >=5 times/h, and the diagnostic criteria are described in the Guidelines for the Multidisciplinary Diagnosis and Treatment of Obstructive Sleep Apnea in Adults[23]; (2) Male patients aged 18~60 years; (3) There is mucosal tissue hypertrophy in the oropharynx, resulting in narrow pharyngeal cavity, hypertrophy or too long uvula, too low and too long soft palate, hypertrophy of tonsils or stenosis of the palate.
Exclusion criteria
Exclusion criteria: (1) BMI > 35 kg/m^2; (2) Patients with central sleep apnea hypopnea; (3) Patients who are allergic to dexmedetomidine or propofol or have a history of seizures; (4) Patients with severe respiratory, cardiovascular, nervous system diseases or poor health conditions; (5) Patients who underwent other upper airway surgery during the study period; (6) Patients with severe maxillofacial deformity.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Fibrolaryngoscopic morphology; | — |
Secondary
| Measure | Time frame |
|---|---|
| Imaging measurement data;Airway pressure; | — |
Countries
China
Contacts
Public ContactDi Zhao
The Second Affiliated Hospital of Zhejiang University School of Medicine
Outcome results
None listed