None
Conditions
Interventions
Remazolam group:Remazolam 0.25mg/kg, 1 minute limited infusion
After sleeping, 0.2mg/kg of micuronium was injected within 30 seconds, and 20ug/kg of afentanil was injected within 30 seconds. The laryngeal mask was inserted and the anesthesia machine was used to c
Propofol group:Propofol 2mg/kg, 1 minute limited infusion
Sponsors
Weifang People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Females aged 18-65 years; 2. Body mass index (BMI) 18-30kg/m^2; 3. ASAI-II level; 4. Patients who intend to undergo gynecological day hysteroscopic surgery under intravenous general anesthesia; 5. No heart and lung diseases, no liver and kidney dysfunction; 6. The patient has good compliance and voluntarily signs the informed consent form for anesthesia.
Exclusion criteria
Exclusion criteria: 1. Patients with obvious respiratory and circulatory dysfunction, abnormal liver and kidney function before surgery; 2. Those who are allergic or contraindicated to benzodiazepines, propofol, opioids and their components; 3. Patients with severe neuropsychiatric diseases and patients who have been taking antidepressants, anxiolytics or other psychotropic drugs for a long time (more than 3 months); 4. Patients with severe hypertension (SBP>180mmHg or DBP>100mmmHg after admission).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Success rate of anesthesia; | — |
Secondary
| Measure | Time frame |
|---|---|
| Time to sleep induced by anesthesia;Time to recover from anesthesia;Duration of anesthesia maintenance;Vital signs at different times ( blood pressure, heart rate, oxygen saturation [ SpO2 ], prtial pressure of end tidal carbon dioxide [PetCO2], respiration rate, [RR]);Adverse events during anesthesia induction (injection pain, hiccup, cough, motility, hypertension, hypotension, tachycardia, bradycardia, etc.);Adverse events during anesthesia maintenance (hiccup, motility, cough, hypertension, hypotension, tachycardia, bradycardia, etc.);PONV incidence; | — |
Countries
China
Contacts
Public ContactJi Fanceng
Weifang People's Hospital
Outcome results
None listed