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Differential diagnosis of glioma recurrence and post-treatment response based on advanced DCE-MRI tracer kinetic models

Differential diagnosis of glioma recurrence and post-treatment response based on advanced DCE-MRI tracer kinetic models

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500097120
Enrollment
Unknown
Registered
2025-02-12
Start date
2022-12-20
Completion date
Unknown
Last updated
2025-02-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Glioblastoma, lymphoma, metastases

Interventions

Glioma recurrence group:None
Glioma pseudoprogression or radionecrosis group:None

Sponsors

Drum Tower Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1.Magnetic resonance imaging was used to detect glioma, which had not been previously treated with any tumor-related surgery or chemoradiotherapy; 2.T1WI, T2WI, FLAIR and T1CE, DWI and DCE scans were performed in MRI; 3.Glioma was pathologically confirmed by surgery or puncture biopsy before chemoradiation; 4.Patients were followed up regularly after starting treatment until relapse or remission; 5.Patients were followed up regularly after starting treatment until relapse or remission;

Exclusion criteria

Exclusion criteria: 1.Patients with suspected glioma who completed the examination but were eventually confirmed by histopathology as non-glioma and who gave up surgery and biopsy without pathologically confirmed glioma; 2.Poor imaging quality (large distortion of image artifacts due to intolerance, poor coordination or other reasons); 3.The lesions were completely cystic, with few solid components, and it was difficult to complete post-image processing;

Design outcomes

Primary

MeasureTime frame
Sensitivity;Specificity;Accuracy;Area Under Curve;

Countries

China

Contacts

Public ContactXin Zhang

Drum Tower Hospital

zhangxin@njglyy.com+86 13814066403

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026