Cognitive dysfunction
Conditions
Interventions
Experimental group:Complimentary study drug
Sponsors
Huashan Hospital, Fudan University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1.>=18 years old; 2. Signed informed consent; 3.Patients treated with GV-971 prescribed by a clinician.
Exclusion criteria
Exclusion criteria: 1.Those who may be allergic to GV-971 capsules as judged by the investigator; 2. Pregnant or lactating women; 3. Unable to cooperate with the completion of the inquiry; 4. Any other disease or condition that, in the opinion of the investigator, is not suitable to participate in this clinical trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of adverse reactions in patients treated with GV-971 during the 48-week and 96-week monitoring periods;Incidence of AE/SAE in patients treated with GV-971 during the 48-week and 96-week monitoring periods; | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence of adverse events and adverse reactions in patients with hepatic insufficiency treated with GV-971;Incidence of adverse events and adverse reactions in patients with renal insufficiency treated with GV-971;GV-971 and commonly used drugs in the elderly, including AD treatment drugs AChEIs and USD Iron, antihypertensive drugs, hypoglycemic drugs, lipid-lowering drugs, anti-platelet aggregation drugs, sedative hypnotic drugs, heart blood The incidence of adverse events and adverse reactions in the population with concomitant use of tube disease drugs);The effect of GV-971 on elderly patients with common comorbidities (including hypertension, diabetes and high fat) was investigated Cardiovascular and cerebrovascular diseases (coronary heart disease, stroke), sleep disorders) (blood pressure, Changes in blood glucose and blood lipid indicators, incidence of cardiovascular and cerebrovascular diseases, and incidence of sleep disorders);Incidence of brainstem encephalitis in patients treated with GV-971;After 48 and 96 weeks of treatment, the scores of Mini-mental state Examination were changed compared with baseline; | — |
Countries
China
Contacts
Public ContactDong Qiang
Huashan Hospital, Fudan University
Outcome results
None listed