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Clinical observation of different doses of fentanyl combined with ciprofol for pediatric bronchoscopy

Clinical observation of different doses of fentanyl combined with ciprofol for pediatric bronchoscopy

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500097084
Enrollment
Unknown
Registered
2025-02-12
Start date
2025-02-20
Completion date
Unknown
Last updated
2025-02-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

pneumonia

Interventions

Group A:Group A received intravenous injection of fentanyl 5ug/kg for 30 seconds. After 2 minutes, a microinjection pump was used to pump 0.4mg/kg of cyclosporine within 1 minute. The examination was
Group B:Group B received intravenous injection of fentanyl at a dose of 10ug/kg for 30 seconds. After 2 minutes, a microinjection pump was used to inject cyclosporine at a dose of 0.4mg/kg within 1 mi
Group C:Group C received intravenous injection of 2ml of physiological saline for 30 seconds. After 2 minutes, a microinjection pump was used to pump 0.4mg/kg of cyclosporine within 1 minute. The exam

Sponsors

Ganzhou Maternal and Child Health Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
No minimum to 18 Years

Inclusion criteria

Inclusion criteria: (1) Children undergoing scheduled bronchoscopy under sedation; (2) ASA Level I-II, age <= 18 years old, male or female not limited; (3) No neurological or psychiatric disorders, no long-term use of sedatives or antidepressants.

Exclusion criteria

Exclusion criteria: There are contraindications for general anesthesia; Known or suspected allergies or contraindications to cyclosporine excipients or opioid drugs; Serious heart, lung, liver, kidney, brain and other major diseases; Has a mental illness.

Design outcomes

Primary

MeasureTime frame
Coughing score during bronchoscopy passing through the glottis and protuberance;heart rate;mean blood pressure (MAP);SPO2;Respiratory depression;Awakening delay;

Secondary

MeasureTime frame
General information: gender, age, body mass index (BMI), ASA grading, HGB and PLT, etc;injection pain;Intraoperative anesthesia effect rating;Operator satisfaction;Operation time of each group of patients (start to end time of operation);Wake up time (the time from the end of surgery to the patient's recovery of orientation);Departure time (the time from the end of the surgery until the patient meets the standard for leaving the room);Total application amount of lidocaine;Application examples of ephedrine;Application examples of atropine;

Countries

China

Contacts

Public ContactQiao Yang

Ganzhou Maternal and Child Health Hospital

992384980@qq.com+86 199 7971 1206

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026