Patients with negative symptoms of schizophrenia
Conditions
Interventions
Pseudo stimulus group:Pseudo-stimulus
Gamma frequency stimulation group:? frequency stimulation
? frequency stimulation group:Theta frequency stimulation
Sponsors
Affiliated Kangning Hospital of Ningbo University
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1.Meets the diagnostic criteria for schizophrenia in The Diagnostic and Statistical Manual of Mental Disorders, 5th edition (DSM-5) in the United States; 2.Age between 18-60 years old, male or female not limited; 3.PANSS score >= 60 points, positive scale score >= 10 points, negative scale score >= 7 points; 4.Willing to participate in this study and sign the informed consent form; 5.The patient's physical examination, medical history, vital signs, blood and urine routine, liver and kidney function, electrolytes, electrocardiogram, electroencephalogram and other indicators are normal.
Exclusion criteria
Exclusion criteria: 1.Has severe impulsivity and suicidal tendencies; 2.There are contraindications for treatment, such as those with metal implants in the skull; 3.Individuals who have received electroconvulsive therapy within the past month; 4.pregnancy; 5.History of alcohol or other psychoactive substance abuse, severe physical illness; 6.Intellectual impairment (IQ<90); 7.Patients with poor hearing or deafness.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| PANSS Scale Evaluation;RBANS Cognitive Scale Assessment;Magnetic resonance imaging; | — |
Secondary
| Measure | Time frame |
|---|---|
| Near infrared functional imaging;Behavioral tasks;EEG changes;Electromyographic changes; | — |
Countries
China
Contacts
Public ContactDongsheng Zhou
Affiliated Kangning Hospital of Ningbo University
Outcome results
None listed