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A randomized controlled trial of ultrasound-guided transversus abdominis plane block versus quadratus lumborum block for postoperative analgesia and sleep quality in elderly patients undergoing abdominal surgery

A randomized controlled trial of ultrasound-guided transversus abdominis plane block versus quadratus lumborum block for postoperative analgesia and sleep quality in elderly patients undergoing abdominal surgery

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500097074
Enrollment
Unknown
Registered
2025-02-12
Start date
2025-03-03
Completion date
Unknown
Last updated
2025-03-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Perioperative sleep disorder

Interventions

Experimental group:In the experimental group, 0.25% ropivacaine hydrochloride was used for quadratus lumborum block, and the lateral approach of quadratus lumborum block was performed. The abdominal w
Control group:The patients in the control group were given 0.25% ropivacaine hydrochloride transversus abdominis plane block, and the patients were placed in the supine position. The abdominal wall wa

Sponsors

Peking University Third Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
60 Years to 90 Years

Inclusion criteria

Inclusion criteria: Elderly patients with age > 60 years, planned to undergo elective abdominal surgery and operation duration > 1 hour

Exclusion criteria

Exclusion criteria: (1) History of mental illness; (2) History of bleeding disorders, abnormal coagulation function (abnormal coagulation indicators or thrombocytopenia), abdominal wall skin infection; (3) Severe liver dysfunction (Child-Pugh grade 3 or above), severe renal dysfunction (preoperative creatinine > 177 umol/L), or American Society of Anesthesiologists (ASA) grade V; (4) Patients with a history of sleep disorders (having taken hypnotic drugs within one month) or obstructive sleep apnea; (5) Patients who refuse postoperative analgesia.

Design outcomes

Secondary

MeasureTime frame
The degree of pain was evaluated at 4, 24 and 48 h after operation;

Primary

MeasureTime frame
Subjective sleep quality score on the first day after surgery;

Countries

China

Contacts

Public ContactBaoLin

Peking University Third Hospital

baolin623ad@163.com+86 183 1003 0160

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026