Sepsis
Conditions
Interventions
Patient Group:None
Healthy Control Group:None
Sponsors
Tangdu Hospital of the Fourth Military Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: Patient Group(1) Aged 18–80 years; (2) Meet the diagnostic criteria of Sepsis 3.0: The patient has an infection with associated organ dysfunction, that is, both of the following criteria 1. and 2. are met: 1. The patient has an infection; 2. The Sequential Organ Failure Assessment (SOFA) score is >= 2 points; (3) The patient or legal guardian agrees to participate in this study and signs the informed consent form. Healthy Control Group 1 Aged 18–80 years; 2 The patient or legal guardian agrees to participate in this study and signs the informed consent form.
Exclusion criteria
Exclusion criteria: Patient Group (1) Individuals under 18 years of age or over 80 years of age; (2) Patients with underlying diseases such as malignant tumors, hematologic disorders, liver or kidney dysfunction, or immune system diseases; (3) Pregnant or breastfeeding patients; (4) Individuals or their legal guardians who refuse to participate in this study. Healthy Control Group (1) Individuals under 18 years of age or over 80 years of age; (2) The patient or legal guardian refuses to participate in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Peripheral Blood Metabolomics;Peripheral Blood Proteomics;Levels of Key Biomarkers in Peripheral Blood;In-hospital Mortality Rate;In-hospital Outcomes;ICU 14-day Survival Rate;28-day Survival Rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Complete Blood Count ;Liver and Kidney Function Tests;Coagulation Parameters;Cardiac Injury Markers; Inflammatory Cytokines; Types of Bacterial Infections;Site of Infection;Duration of Infection;Average Duration of Mechanical Ventilation;Average Length of Stay in General Ward;Average Length of Stay in ICU; Average Duration of Hemodialysis;Sequential Organ Failure Assessment (SOFA) Score;Acute Physiology and Chronic Health Evaluation II (APACHE-II) Score; | — |
Countries
China
Contacts
Public ContactLi-Nong Yao
Tangdu Hospital of the Fourth Military Medical University
Outcome results
None listed