Atrial fibrillation combined with heart failure with preserved ejection fraction
Conditions
Interventions
Gold Standard:Left atrial pressure directly measured through transseptal puncture during atrial fibrillation radiofrequency ablation procedure. This is currently the most accurate clinical method for
Index test:Mean pixel value of left atrial region measured by functional dynamic digital radiography
Sponsors
Peking Union Medical College Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1.Non-valvular AF patients aged 18-80 years; 2.Meeting HFpEF diagnostic criteria: a. H2FPEF score >= 6 points, and b. Left ventricular ejection fraction >= 50%; 3.Left atrial enlargement: a. Left atrial volume index > 34 mL/m², or b. Left atrial anteroposterior diameter > 39 mm (male) / > 38 mm (female); 4.Planned for radiofrequency ablation; 5.Signed informed consent.
Exclusion criteria
Exclusion criteria: 1.Intracardiac thrombus detected by transesophageal echocardiography; 2.Hyperthyroidism; 3.Tumors or other diseases requiring treatment with life expectancy less than 1 year; 4.Conditions affecting left atrial imaging assessment, such as significant pleural effusion, active pulmonary infection, mediastinal mass, severe chest wall deformity, etc; 5.Pregnancy; 6.Other conditions that may affect the evaluation of study results.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Left atrial mean pixel value; | — |
Secondary
| Measure | Time frame |
|---|---|
| Left ventricular mean pixel value; | — |
Countries
China
Contacts
Public ContactXinglin Yang
Peking Union Medical College Hospital
Outcome results
None listed