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A comparative study of the effect of Er:YAG laser and cortical-perforation technique in tooth extraction cases of patients with potential risk of medication-related osteonecrosis of the jaw

A comparative study of the effect of Er:YAG laser and cortical-perforation technique in tooth extraction cases of patients with potential risk of medication-related osteonecrosis of the jaw

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500097058
Enrollment
Unknown
Registered
2025-02-11
Start date
2024-08-23
Completion date
Unknown
Last updated
2025-02-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients with a history of using anti bone resorption drugs and/or anti angiogenic drugs, and whose bodies can tolerate tooth extraction surgery

Interventions

bone tube technology group:bone tube technology
Er: YAG laser surgery group:Er: YAG laser surgery

Sponsors

China-Japan Friendship Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. History of using anti bone resorption drugs and/or anti angiogenic drugs; 2. The body can tolerate tooth extraction surgery; 3. Chronic inflammation in the mouth (such as chronic periodontitis or periapical periodontitis) or teeth without preservation significance; 4. After evaluation, the use of anti bone resorption or anti angiogenesis drugs can be suspended for at least 6 weeks during the drug suspension window period; 5. Age over 18 years old;

Exclusion criteria

Exclusion criteria: 1. History of Head and Neck Radiotherapy; 2. Individuals with a history of primary or metastatic malignant tumors in the oral or jawbone; 3. Individuals whose overall condition cannot tolerate surgery; 4. Children (under 18 years old) or pregnant patients;

Design outcomes

Primary

MeasureTime frame
Early Wound-Healing Index(EHI);

Secondary

MeasureTime frame
Subjective indicator pain evaluation: Visual Analog Rating Scale;Is there redness and swelling of the oral mucosa, and bone exposure;Complications: safety indicators such as maxillary sinus perforation and inferior alveolar nerve injury;

Countries

China

Contacts

Public ContactZhu Wenxuan

China-Japan Friendship Hospital

zhwenxuan1991@126.com+86 13366620792

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026