Atrial fibrillation
Conditions
Interventions
Intracardiac echocardiography guided left atrial appendage occlusion group:Treat left atrial appendage thrombus by left atrial appendage occlusion via the guidance of intracardiac echocardiography
Sponsors
The First Affiliated Hospital of Ningbo University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1) Patients with non-valvular atrial fibrillation aged >=18 years; 2) the presence of left atrial appendage thrombus confirmed by esophageal ultrasound; 3) one of the following conditions: (1) left atrial appendage thrombosis is still present after continuous treatment with at least one anticoagulant drug at a standard dose for not less than 6 weeks; (2) there are contraindications to anticoagulant drug treatment; (3) the patient refuses to accept anticoagulant drug treatment and requires left atrial appendage occlusion; 4) Subjects or their legal representatives voluntarily participate in the trial and sign a written informed consent form.
Exclusion criteria
Exclusion criteria: (1) valvular atrial fibrillation; (2) left atrial appendage thrombus prominent to the left atrium, or preprocedural imagine indicates that it is not suitable to perform left atrial appendage occlusion; (3) coexistence with left atrial thrombus; (4) myocardial infarction, ischemic stroke, or transient ischemic attack within 30 days; (5) sever heart failure, renal disfunction, or liver disfunction; (6) life expectancy less than 1 year.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Periprocedural major adverse events; | — |
Secondary
| Measure | Time frame |
|---|---|
| Periprocedural minor adverse events; | — |
Countries
China
Contacts
Public ContactHuimin Chu
The First Affiliated Hospital of Ningbo University
Outcome results
None listed