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Determination of the 95% Effective Initial Dose in dural puncture epidural for labor analgesia

Determination of the 95% Effective Initial Dose in dural puncture epidural for labor analgesia

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500097052
Enrollment
Unknown
Registered
2025-02-11
Start date
2025-02-16
Completion date
Unknown
Last updated
2025-02-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

labor analgesia

Interventions

dural puncture epidural group (group D):The initial dose for the first parturient was 8 mL of 0.08% ropivacaine + 0.3 µg/mL sufentanil. A Numeric Rating Scale (NRS) score of <4 within 20 minutes was c
if the effect was satisfactory, the initial dose for the next parturient was determined by computer randomization, with a 5% probability of reducing the dose by 2 mL and a 95% probability of maintaini
epidural block group (group E):The initial dose for the first parturient was 10 mL of 0.08% ropivacaine + 0.3 µg/mL sufentanil. A Numeric Rating Scale (NRS) score of <4 within 20 minutes and an anesth

Sponsors

The Third Affiliated Hospital of Zhengzhou University
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
20 Years to 36 Years

Inclusion criteria

Inclusion criteria: American Society of Anesthesiologists Physical Status I or ?, who were at full term with a singleton fetus in vertex presentation, aged 20-36yr, with body mass index of 21-35 kg/m^6, and with cervical dilation 1- 3cm, primipara

Exclusion criteria

Exclusion criteria: (1) Contraindications for neuraxial labor analgesia; (2) Hypertension in pregnancy and gestational diabetes; (3) Known fetal anomalies; (4) History of chronic pain or use of psychiatric medications during pregnancy; (5) Allergy to opioids or local anesthetics.

Design outcomes

Primary

MeasureTime frame
NRS Score;NRS Score;

Secondary

MeasureTime frame
Modified Bromage Score;

Countries

China

Contacts

Public ContactJi Leting

The Third Affiliated Hospital of Zhengzhou University

jlt0001@126.com+86 185 3800 6729

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026