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To explore the clinical observation effect of Huanxiaozhiqiu decoction on airway function and consititution in children CARAS based on the effect of lung and spleen treatment

To explore the clinical observation effect of Huanxiaozhiqiu decoction on airway function and consititution in children CARAS based on the effect of lung and spleen treatment

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500097029
Enrollment
Unknown
Registered
2025-02-11
Start date
2025-03-01
Completion date
Unknown
Last updated
2025-02-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Combined allergic rhinitis asthma syndrome

Interventions

experimental group:Huanxiaozhiqiu decoction

Sponsors

Dongfang Hospital Beijing University of Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
6 Years to 14 Years

Inclusion criteria

Inclusion criteria: 1. Children aged 6-14 years old. 2. The diagnostic criteria for CARAS in children were met, and the clinical stage was non-acute attack, in which the degree of asthma was graded as grade 3, and theTraditional Chinese Medicine pattern was "qi deficiency and phlegm stasis". 3. Parents and/or the child himself/herself (dual signatures required if =8 years of age) give informed consent to follow the physician's diagnostic and therapeutic arrangements and to voluntarily enroll in the study by signing the informed consent form.

Exclusion criteria

Exclusion criteria: 1. Combined with serious respiratory infectious diseases; combined with serious primary diseases such as cardiovascular, hepatic, renal, endocrine or hematopoietic systems; combined with other nasal diseases such as sinusitis, vasomotor rhinitis, nasal polyps, deviated septum and so on. 2. Comorbid neurological or psychiatric disorders resulting in cognitive impairment or communication disorders. 3. Those who are unable to cooperate with the nitric oxide examination of exhaled breath; and those who are unable to cooperate with the examination of the pulmonary ventilation function of children due to the combination of otitis media perforation, pneumothorax, inguinal hernia, or ophthalmic surgery of the chest or abdomen in the past 1-3 months. 4. Allergic to therapeutic drugs. 5. Those who have received other relevant treatments that may affect the observed effects of this study or participated in other experimental studies within the last 3 months.

Design outcomes

Primary

MeasureTime frame
Pulmonary function small airway indexes;disease control rate(%);CARAS symptom rating scales;constitution assessment of children with asthma;circumstance of respiratory infections;

Secondary

MeasureTime frame
asthma control test;allergic rhinitis symptom scales;other pulmonary ventilation indexes;FeNO test;visual analog scale;safety indicators;

Countries

China

Contacts

Public ContactLiqun Wu

Dongfang Hospital Beijing University of Chinese Medicine

Wulq1211@163.com+86 131 6427 2790

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026