Comparisons of Multilevel Transversus Abdominis Plane Blocks and Transversalis Fascia Plane Block for Postoperative Analgesia in Lower Uterine Segment Caesarean Section

A Randomized, Observer-Blinded, Controlled Trial Comparing Multilevel Transversus Abdominis Plane Blocks and Transversalis Fascia Plane Block for Postoperative Analgesia in Lower Uterine Segment Caesarean Section

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2500097026

Enrollment

Unknown

Registered

2025-02-11

Start date

2025-02-15

Completion date

Unknown

Last updated

2025-02-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Full-term women undergoing caesarean section with transverse incision of lower uterine segment

Interventions

Traditional Transversus Abdominis Plane Block :Transversus abdominis plane block (at the umbilical level)

Transversalis fascia plane block:Transversalis fascia plane block

Modified transversus abdominis plane block group:Transversus abdominis plane block (a level in-between the umbilical and the iliac crest levels)

Eligibility

Sex/Gender

Female

Age

18 Years to 40 Years

Inclusion criteria

Inclusion criteria: Full-term parturients (gestational age >= 37 weeks, singleton pregnancy); Elective cesarean section with a transverse incision in the lower uterine segment; Aged between 18 and 40 years old; Classified as grade II or III according to the American Society of Anesthesiologists (ASA) classification criteria; Consent to participate in this study.

Exclusion criteria

Exclusion criteria: Neuropsychiatric diseases; History of addiction to sedatives and analgesics; Hepatic and renal insufficiency; Severe cardiac, pulmonary or cerebral diseases; Abnormal blood coagulation function; Infection or damage at the puncture site; Peripheral neuropathy; Allergy to local anesthetics; Morbid obesity [body mass index (BMI) > 40]

Design outcomes

Primary

Measure	Time frame
Hydromorphone consumption in 8h after surgery;	—

Secondary

Measure	Time frame
The number of effective and total pressing times of PCA from 0 to 6h and from 0 to 12h after block;time of the first pressing on PCA ;Hydromorphone consumption from 0 to 12h after nerve block;Resting pain VAS score and motor pain VAS score at 30min, 2, 4, 8, 10 and 12h after nerve block;Area under the pain intensity-time curve at rest and during exercise from 0 to 12h after nerve block;The number of adverse reactions such as nausea, vomiting, hypotension, hypoxemia, and dizziness within 12h after nerve block;At 24h after nerve block, subjects rated their overall satisfaction with analgesia;	—

Measure

Time frame

The number of effective and total pressing times of PCA from 0 to 6h and from 0 to 12h after block;time of the first pressing on PCA ;Hydromorphone consumption from 0 to 12h after nerve block;Resting pain VAS score and motor pain VAS score at 30min, 2, 4, 8, 10 and 12h after nerve block;Area under the pain intensity-time curve at rest and during exercise from 0 to 12h after nerve block;The number of adverse reactions such as nausea, vomiting, hypotension, hypoxemia, and dizziness within 12h after nerve block;At 24h after nerve block, subjects rated their overall satisfaction with analgesia;

—

Countries

China

Contacts

Public ContactYuan Kaiming

The Second Affiliated Hospital of Wenzhou Medical University

yuankm_wh@163.com+86 138 1970 8274

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026