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Improvement of Outcomes in Patients with Sepsis by Bacillus Licheniformis: A Prospective, Randomized, Controlled Clinical Trial

Improvement of Outcomes in Patients with Sepsis by Bacillus Licheniformis: A Prospective, Randomized, Controlled Clinical Trial - Improvement of Outcomes in Patients with Sepsis by Bacillus Licheniformis

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500097016
Enrollment
Unknown
Registered
2025-02-11
Start date
2025-02-12
Completion date
Unknown
Last updated
2025-02-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Sepsis

Interventions

Experimental Group:All patients were treated in accordance with the Chinese Guidelines for the Emergency Treatment of Sepsis/Septic Shock (2018), which includes early fluid resuscitation, correction o
Control Group:All patients were treated in accordance with the Chinese Guidelines for the Emergency Treatment of Sepsis/Septic Shock (2018), which includes early fluid resuscitation, correction of ele

Sponsors

Fujian Medical University Union Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: (1) Age is 18 years or older; (2) Diagnosed with sepsis. Patients who meet the diagnostic criteria for sepsis and septic shock as defined by Sepsis 3.0 will be included; (3) Patients have received standardized treatment for sepsis.

Exclusion criteria

Exclusion criteria: (1) Active malignant tumor or history of malignant tumor and currently using anti-tumor drugs; (2) Acquired immunodeficiency syndrome; (3) History of autoimmune diseases; (4) Combined with enterostomy; (5) Gastrointestinal bleeding or liver cirrhosis; (6) End-stage renal disease or history of hemodialysis; (7) Cardiopulmonary resuscitation before hospital admission; (8) Poisoning; (9) Pregnancy and peripartum period; (10) Use of antibiotics in the past 3 months.

Design outcomes

Primary

MeasureTime frame
ICU Hospitalization Duration;

Secondary

MeasureTime frame
28-day mortality rate;Recovery of Organ Function;Readmission Rate;Long-term Disability Status;

Countries

China

Contacts

Public ContactYue Chen

Fujian Medical University Union Hospital

cyxh@fjmu.edu.cn+86 180 5971 4706

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026