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Efficacy and safety of fospropofol disodium for anesthesia induction in patients with tracheotomy weakness during reoperation

Efficacy and safety of fospropofol disodium for anesthesia induction in patients with tracheotomy weakness during reoperation

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500097007
Enrollment
Unknown
Registered
2025-02-11
Start date
2025-02-17
Completion date
Unknown
Last updated
2025-02-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Tracheotomy reoperation patients

Interventions

Experimental group:Intravenous injection of propofol disodium 10 mg/kg
Control group:Intravenous injection of remifentanil 0.2mg/kg

Sponsors

Sichuan Bayi Rehabilitation Center (Sichuan rehabilitation hospital)
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 74 Years

Inclusion criteria

Inclusion criteria: 1. Age 18-74 years old; 2.ASA grade IV; 3.modified frailty index (MFI) score >= 3; 4. all operations were performed under general anesthesia.

Exclusion criteria

Exclusion criteria: 1. Have a history of allergy to analgesic or sedative drugs; 2. have a history of using benzodiazepines in the past month; 3. have myasthenia gravis; 4. uncontrolled grade 3 hypertension; 5. have fever or uncontrolled pulmonary infection.

Design outcomes

Primary

MeasureTime frame
Mean arterial pressure;heart rate;—

Secondary

MeasureTime frame
Pain;bucking;Onset time of anesthesia;—

Countries

China

Contacts

Public ContactZhao Zeyu

Sichuan Bayi Rehabilitation Center (Sichuan rehabilitation hospital)

gyzhaozy@163.com+86 180 1131 0198

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026