Malignant hematological diseases after autologous hematopoietic stem cell transplantation
Conditions
Interventions
Group Romiplostim N01:Romiplostim No1 Treatment
Sponsors
The first affiliated hostipal of nanchang university
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Patients who are receiving autologous hematopoietic stem cell transplantation for malignant hematological diseases (including multiple myeloma, lymphoma, and acute leukemia with good prognosis); 2. Weight >=30kg, regardless of age or gender; 3. ECOG score <=1; 4. Patients is eligible for follow-up; 5. Patients without serious functional damage of major organs was found in the whole body; 6. Patients voluntarily sign informed consent forms.
Exclusion criteria
Exclusion criteria: 1.Have serious organ dysfunction or disease, such as heart, liver, kidney, pancreas and other serious disease and dysfunction; 2.Patients who cannot tolerate subcutaneous injections of Romiplostim N01; 3.Any life-threatening disease, medical condition, or organ system dysfunction that the investigator believes could compromise the safety of the subject or put the results of the study at unnecessary risk; 4.Patients who was drug dependent or uncontrolled mental illness or with cognitive disabilities; 5.Joined other similar clinical investigators within 3 months; 6.Other conditions not suitable for inclusion evaluated by the investigator (such as patients who are expected to be unable to adhere to treatment due to financial problems, etc.).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The time of platelet engraftment; | — |
Secondary
| Measure | Time frame |
|---|---|
| Platelet engraftment rate within 28 days after transplantation;Platelet transfusion volume;The occurrence situation of adverse events and serious adverse events;Incidence and severity of bleeding events;The incidence rate of secondary thrombocytopenia events during the follow-up period;Overall survival;Progression free survival;Disease free survival;Obejctive response rate; | — |
Countries
China
Contacts
Public ContactFei Li
The first affiliated hostipal of nanchang university
Outcome results
None listed