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Effect of accelerated intermittent theta burst magnetic stimulation with different parameters on adolescent depression

Effect of accelerated intermittent theta burst magnetic stimulation with different parameters on adolescent depression

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500096997
Enrollment
Unknown
Registered
2025-02-10
Start date
2025-02-16
Completion date
Unknown
Last updated
2025-02-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Depressive episode

Interventions

Conventional treatment group A:Classic repetitive transcranial magnetic stimulation therapy was performed for 14 days
Acceleration group B:3 times/day, 50min/ time interval, 1800 pulses/time.The treatment lasted for 7 days
Acceleration group C:3 times/day, 50min/ time interval, 3600 pulses/time.The treatment lasted for 7 days
Acceleration group D:6 times/day, 50min/ time interval, 1800 pulses/time.The treatment lasted for 7 days
Acceleration group E:3 times/day, 30min/ time interval, 1800 pulses/time.The treatment lasted for 7 days

Sponsors

Guizhou Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
12 Years to 24 Years

Inclusion criteria

Inclusion criteria: (1) Meet the DSM-5 diagnostic criteria for major depressive disorder; (2) Right-handed, EEG normal; (3) Age 12-19 years old; (4) Montgomery-Eisenberg Depression Scale (MADRS) =22 points; (5) Patients took a single selective serotonin reuptake inhibitor during treatment; (6) Informed consent and signed informed consent by both patient and guardian; ? Get the approval of the Ethics committee.

Exclusion criteria

Exclusion criteria: 1 Suspected or confirmed schizophrenia spectrum and other psychiatric disorders, bipolar disorder, psychoactive substance use history; 2 Have a history of brain surgery; 3 A history of epilepsy and family history; 4 Patients with severe headache, hypertension, malignant tumor, open wound, vascular embolism, leukopenia, infectious diseases, etc.; 5 Those who have metal or electronic devices built into their bodies.

Design outcomes

Primary

MeasureTime frame
Montgomery-eisenberg depression Scale;Near-infrared brain function to detect language fluency task;

Secondary

MeasureTime frame
scale for suicide ideation;

Countries

China

Contacts

Public ContactZheng Lei

Affiliated Hospital of Guizhou Medical University

1173765117@qq.com+86 183 0258 2420

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026