Effects of Inhaled Nitric Oxide on Lung Physiology Assessed by Electrical Impedance Tomography in Patients with Acute Respiratory Distress Syndrome Receiving High-Flow Oxygen Therapy : A Pilot Study

The value of EIT monitoring to guide NO inhalation in the treatment of postoperative hypoxemia in cardiac surgery patients

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2500096993

Enrollment

Unknown

Registered

2025-02-10

Start date

2025-02-10

Completion date

Unknown

Last updated

2025-02-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute Respiratory Distress Syndrome

Interventions

HFOV combine iNO group:None

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: (1) Diagnosed with ARDS(oxygenation index = 18 years; (4) Willing to participate in the study, having signed the informed consent form, with good compliance and cooperation during follow-up.

Exclusion criteria

Exclusion criteria: (1) Pregnant women; (2) Patients with contraindications to the use of nitric oxide (NO); (3) Body mass index (BMI) >= 35 kg/m²; (4) Patients with refractory shock or severe cardiac dysfunction; (5) Patients with thoracic deformities, massive pleural effusion, pneumothorax, or chest skin damage; (6) Patients with implanted pacemakers; (7) Patients deemed unsuitable for inclusion by the investigators.

Design outcomes

Primary

Measure	Time frame
Overall regional ventilation/perfusion ratio ;	—

Secondary

Measure	Time frame
Overall regional dead space fraction;Overall regional shunt fraction;Oxygenation Index;Vital signs;	—

Countries

China

Contacts

Public ContactLu Weihua

The First Affiliated Hospital of Wannan Medical College (Yijishan Hospital of Wannan Medical College)

lwh683@126.com+86 139 5537 0637

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026