stroke
Conditions
Interventions
Transcranial ultrasound group:Daily interventions include 10 minutes of low-intensity transcranial ultrasound therapy and 80 minutes of conventional rehabilitation training.
Sham stimulation group:Daily interventions include 10 minutes of sham transcranial ultrasound stimulation and 80 minutes of conventional rehabilitation training
Sponsors
Sir Run Run Shaw Hospital, Zhejiang University School of Medicine
Eligibility
Sex/Gender
All
Age
40 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1: Aged 40 to 75 years (inclusive of boundary values). 2: Patients with a confirmed diagnosis of first-time stroke through CT or MRI imaging, in accordance with the World Health Organization's definition of stroke. 3: Onset of the stroke between 1 and 6 months. 4: Brunnstrom stage III and above, excluding patients with severe disabilities who are unable to complete the training. 5: Montreal Cognitive Assessment (MoCA) score of >=26 points. 6: Voluntarily participating in the study and signing an informed consent form.
Exclusion criteria
Exclusion criteria: 1: Comorbidities affecting functional recovery, such as heart, lung, liver, kidney, and hematological system diseases. 2: Severe consciousness impairment. 3: A history of or concurrent conditions affecting motor function, such as fractures, trauma, or surgical wounds. 4: Presence of cranial defects or intracranial metal implants. 5: Vulnerable populations, including individuals with mental illnesses, cognitive impairments, critically ill patients, and pregnant women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Fugl-Meyer motor function assessment ;Gait parameters ;resting motor threshold, RMT;motor evoked potential, MEP; | — |
Secondary
| Measure | Time frame |
|---|---|
| Berg Balance Scale, BBS;Modified Rankin Scale, mRS;stroke impact scaleSIS; | — |
Countries
China
Contacts
Public ContactHao Xiong
Sir Run Run Shaw Hospital, Zhejiang University School of Medicine
Outcome results
None listed