Cerebrovascular disease
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Age>=18 years; 2. Pre-stroke mRS<=2; 3. Evidence of distal medium vascular occlusion defined as occlusion of the non-dominant M2 segment* /M3/M4segment of the MCA, the ACA (A1, A2, or A3 segments), or the PCA (P1, P2 or P3 segments) confirmed by CTA/MRA/DSA; 4.Time from symptom onset to treatment <24 hours; 5.Informed consent obtained from patient or acceptable patient surrogate.
Exclusion criteria
Exclusion criteria: 1) neuroimaging evidence of cerebral hemorrhage on presentation; 2) patients who had primary proximal large vessel occlusion, multivessel occlusion, missing baseline mRS scores, or missing clinical variables were excluded from the analysis. 3) serious, advanced, or terminal illness.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Modified Rankin Scale (mRS) score at 90 days;Symptomatic intracranial hemorrhage at 24 hours; | — |
Secondary
| Measure | Time frame |
|---|---|
| Mortality at 90 days;Ratio of 90-day mRS <= 2 or 90-day mRS <= 1; | — |
Countries
China
Contacts
Department of Neurology, The First Affiliated Hospital of University of Science and Technology of China