Painless gastrointestinal endoscopy anesthesia
Conditions
Interventions
Rimazzolam group (group R):Sufentanil (0.1ug/kg) was injected intravenously, and Rimazzolam was given 1mg/ time after 3 minutes, with intermittent intravenous injection (following the principle of ind
Propofol group (group P):Intravenous sufentanil (0.1ug/kg), propofol 10 mg/ time after 3 minutes, and intermittent intravenous injection (following the principle of individualization) until the preset
Sponsors
People's Hospital of Ningxia Hui Autonomous Region
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: (1) Outpatients who undergo painless gastrointestinal endoscopy in the Digestive Endoscopy Center; (2) Age 18~60 years old, gender is not limited; (3) BMI28~40 kg/m^2;(4) ASA grade I and II; (5) Have normal cognitive and communication skills; (6) Voluntarily sign to be informed.
Exclusion criteria
Exclusion criteria: (1) Severe respiratory, circulatory or endocrine diseases (severe hypertension, unstable angina pectoris, asthma attack, etc.); (2) Coagulation dysfunction; (3) With abnormal functions of important organs such as heart, lung, liver and kidney; (4) Contraindications for the use of propofol, ramizolam and other narcotic drugs; (5) Long-term use of sedative and analgesic drugs; (6) Acute upper gastrointestinal bleeding or gastrointestinal perforation; (7) Have a history of respiratory tract infection in recent 2 weeks; (8) Psychosocial diseases or cognitive dysfunction.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of intraoperative hypoxemia (< 90%) and severe hypoxemia (< 85%).; | — |
Secondary
| Measure | Time frame |
|---|---|
| Success rate of entering the mirror;SpO2 at different time points;The patient's performance when the first entry was successful and the reasons why the patient failed in the first entry.;The evaluation of sedation effect, anesthesia induction time, gastroscopy time, anesthesia recovery time, hospital leave time and sedative dosage were recorded.;Patient comfort, patient satisfaction and physician satisfaction scores within 24 hours after gastroscopy.;Adverse reactions during and after gastroscopy, postoperative memory of the examination process and postoperative delirium 72 hours later.;Mean arterial pressure at different time points;Heart rate at different time points; | — |
Countries
China
Contacts
Public ContactWang Yun
People's Hospital of Ningxia Hui Autonomous Region
Outcome results
None listed