Esophageal malignancy
Conditions
Interventions
Patients with locally advanced esophageal squamous cell carcinoma:None
Sponsors
Beijing Friendship Hospital affiliated to Capital Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1) Age > 18 years old; 2) Patients with cT2N+M0 or cT3-cT4NanyM0 esophageal squamous cell carcinoma; 3) Patients who have not received any anti-tumor treatment in the past, including but not limited to surgery, radiotherapy, chemotherapy, immunotherapy, targeted therapy, etc.; 4) Able to provide tissue and blood samples for biological analysis; 5) Voluntarily sign the informed consent form (or signed by the legal representative) to prove that they understand the purpose of the study and the operations required for the study and are willing to participate in the study
Exclusion criteria
Exclusion criteria: 1) Aged > 70 years, or with severe comorbidities, such as cardiovascular and cerebrovascular diseases that affect surgery; 2) Previous history of malignant tumors, or received chemotherapy, radiotherapy, molecular targeted therapy, or Chinese medicine treatment and other anti-tumor treatments before enrollment; 3) Preoperative examinations indicate that the tumor may invade the main trachea, heart or large blood vessels; 4) Allergic to the active ingredients or excipients of the drug in this study; 5) Pregnant or lactating patients. 6) Other situations that the researchers believe are not suitable for enrollment
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Overall survival;Disease-free survival; | — |
Secondary
| Measure | Time frame |
|---|---|
| pCR;MPR; | — |
Countries
China
Contacts
Public ContactYong Cui
Beijing Friendship Hospital affiliated to Capital Medical University
Outcome results
None listed