Unilateral multifocal pulmonary edema
Conditions
Interventions
Control Group:none
Sponsors
The First Affiliated Hospital of Wenzhou Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Patients aged 18 to 75 years. 2. Patients who are scheduled to undergo elective thoracoscopic cardiac surgery and require single-lung ventilation. 3. American Society of Anesthesiologists (ASA) grade II or III. 4. Patients voluntarily participated in the study and signed the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Severe chronic obstructive pulmonary disease (COPD) or restrictive lung disease. 2. Allergy to nitric oxide or its device components. 3. Pregnant or lactating women. 4. Severe liver or kidney dysfunction. 5. Participation in other clinical trials in the past 30 days. 6. History of pulmonary arterial hypertension.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Whether there is postoperative unilateral re-expansion pulmonary edema; | — |
Secondary
| Measure | Time frame |
|---|---|
| Oxygenation index (PaO2/FiO2), CCU stay time, postoperative mechanical ventilation time, incidence of postoperative pulmonary complications;IL-6, TNF-a, syndecan-1; | — |
Countries
China
Contacts
Public Contactweijian wang
The First Affiliated Hospital of Wenzhou Medical University
Outcome results
None listed