Postoperative delirium
Conditions
Interventions
R group:0.25% Ropivacaine 20ml
D group:Dexmedetomidine 1ug/kg + 0.25% ropivacaine total 20ml
Sponsors
Ningxia Hui Autonomous Region People's Hospital
Eligibility
Sex/Gender
All
Age
60 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1) Age 60-80 years old and ASA grade I-III; 2) Suitable for regional anesthesia 3) Pass the review of the ethics committee and sign the informed consent.
Exclusion criteria
Exclusion criteria: 1) The corresponding education level of MMSE shall not be lower than the corresponding score (illiteracy > = 17 points, primary school > = 20 points, secondary school and above > = 24 points) 2) patients who refuse to participate in the study; 3) History of previous dementia or psychiatric illness, current use of sedatives or antidepressants 4) Long-term alcoholics or psychotropic drug addicts; 5) Those who are allergic to anesthetic drugs; 6) Other circumstances that the attending physician or investigator considers unsuitable to participate in this study; The reason needs to be documented 7) Patients with severe arrhythmia before surgery, or those with sinus bradycardia shown by electrocardiogram; 8) Participants in other investigators at the same time; 9) Severe visual or hearing impairment;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postoperative delirium; | — |
Secondary
| Measure | Time frame |
|---|---|
| Intraoperative doses of opioids were administered;VAS;Use of analgesic drugs in the 24 hours after surgery;Postoperative NRS pain score;Intraoperative vital signs;Sleep disruption due to pain;Incidence of postoperative adverse reactions such as nausea, vomiting, dizziness and urinary retention;Incidence of local anesthesia poisoning;The incidence of nerve block complications such as infection, bleeding and nerve injury at puncture site;Number and dose of intraoperative vasoactive drugs; | — |
Countries
China
Contacts
Public ContactZhenhai Ye
Ningxia Hui Autonomous Region People's Hospital
Outcome results
None listed