osteoarthritis
Conditions
Interventions
Dex group:After spinal anesthesia, dexmedetomidine was pumped to assist sedation during operation.
Rem group:After spinal anesthesia, Remazolam was pumped to assist sedation during operation.
Sponsors
The First Affiliated Hospital of Shihezi University Medical College
Eligibility
Sex/Gender
All
Age
65 Years to 90 Years
Inclusion criteria
Inclusion criteria: (1) Age over 65, regardless of sex; (2)ASAI-II, with no history of major systemic diseases; (3) preoperative PSQI score > 6 (sleep disorder); (4) Patients who intend to undergo joint replacement under spinal anesthesia; (5) Be able to cooperate with the perioperative sleep quality assessment and sign the informed consent.
Exclusion criteria
Exclusion criteria: (1) allergic to local anesthetics and dexmedetomidine and rimazolam; (2) People with communication disorder and mental disorder; (3) Severe arrhythmia (pacemaker, sick sinus syndrome, severe bradycardia (< 50 beats/min) or more than second degree atrioventricular block); (4) recent use of antipsychotics, alcoholism or drug abuse; Complicated with serious cardiovascular, liver and kidney diseases and cerebrovascular accidents.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| RCSQ score on the first night after operation; | — |
Secondary
| Measure | Time frame |
|---|---|
| Recovery Quality 15 Item Scale;Visual Analogue Scale, VAS;Occurrence of adverse reactions;Hemodynamic indexes;Intraoperative sleep monitoring band data;Intraoperative BIS value; | — |
Countries
China
Contacts
Public ContactHehaichuan
The First Affiliated Hospital of Shihezi University Medical College
Outcome results
None listed