PCOS
Conditions
Interventions
LE group:Routine antagonist protocol combined with letrozole for ovulation induction. Letrozole 2.5mg once per day starts from ovulation stimulation day and continues until HCG injection day.
Control group:Routine antagonist protocol
Sponsors
Sun Yat sen Memorial Hospital
Eligibility
Sex/Gender
Female
Age
No minimum to 42 Years
Inclusion criteria
Inclusion criteria: (1) Women under the age of 42; (2) There are medical indications for IVF/ICSI treatment, and this is the first/second IVF/ICSI treatment; (3) Women diagnosed with PCOS according to Rotterdam criteria; The diagnostic criteria for PCOS are: 1) infrequent ovulation/anovulation; 2) Clinical Kaohsiung/Biochemical Kaohsiung; 3) Polycystic changes in the ovaries; The above three criteria meet any two criteria and exclude other diseases that cause hyperandrogenicity (congenital adrenal hyperplasia, Cushing's syndrome, tumors that secrete androgens, etc.). (4) Obtain written informed consent.
Exclusion criteria
Exclusion criteria: (1) Repeated implantation failures (previous 3 or more IVF/ICSI-ET failures); (2) Untreated endometrial disease; (3) Existence of hydrosalpinx without surgical correction; (4) Diagnosed as endometriosis (stage III or IV); (5) Using donated oocytes to aid in pregnancy; (6) Accepting pre implantation genetic testing; (7) History of recurrent spontaneous abortion.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| clinical pregnancy rate per initial ovulation induction cycle ; | — |
Countries
China
Contacts
Public ContactYu Li
Sun Yat-sen memorial hospital
Outcome results
None listed