Non obstructive coronary heart disease
Conditions
Interventions
Intervention group:Combining conventional drug therapy with cardiac rehabilitation training
Control group:Conventional drug therapy
Sponsors
The Second Affiliated Hospital of Harbin Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: (1) Age 18-75 years old; (2) Patients with confirmed diagnosis of INOCA, the diagnostic criteria for INOCA are: 1) Symptoms of myocardial ischemia, angina pectoris, exertional dyspnea during exertion or at rest; 2) no obstructive coronary artery disease (coronary artery stenosis confirmed by coronary angiography or coronary CTA examination <50%); 3) Evidence of coronary microcirculatory disorders: myocardial stress perfusion scan (CT-MPI) examination determined myocardial blood flow (MBF) <100; (3) No limitation of mobility, able to complete cardiopulmonary exercise test; (4) Ability to use a smartphone; (5) Able to cooperate with the completion of the trial and sign the informed consent form.
Exclusion criteria
Exclusion criteria: (1) Presence of valvular heart disease (aortic stenosis, aortic regurgitation, etc.), (2) cardiomyopathy (hypertrophic, dilated, restrictive, etc.), (3) 50% of patients with EF < cardiac ultrasound, (4) Central nervous system disease (hemorrhagic stroke, ischemic stroke) or undergoing intracranial or spinal cord surgery, (5) Malignant tumors or expected survival time of less than 1 year; (6) The subject is not suitable to participate in this trial (such as suffering from motor restriction diseases); (7) Populations that are unable to understand and/or comply with the procedures of this study (such as patients with alcoholism, drug abuse, or psychiatric disorders); (8) People who are participating in clinical trials of other devices or drugs and have not met the primary endpoint; (9) researchers involved in the design and execution of this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Seattle Angina Questionnaire (SAQ); | — |
Secondary
| Measure | Time frame |
|---|---|
| Readmission due to angina attack;Anxiety levels;Depression levels;Quality of life situation;Sleep quality; | — |
Countries
China
Contacts
Public ContactJian Wu
The Second Affiliated Hospital of Harbin Medical University
Outcome results
None listed