Corneal Blindness
Conditions
Interventions
The MIOK Keratoprosthesis One-Stage Implantation Group:None
The MIOK Keratoprosthesis Two-Stage Implantation Group:None
Sponsors
Chinese PLA General Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1.Age >= 18 years. 2.Monocular or bilateral corneal blindness (according to the World Health Organization's criteria for blindness). 3.Multiple failures of conventional corneal transplant surgeries (the most common indication). 4.High-risk corneal transplant patients who are not suitable for conventional penetrating keratoplasty, such as those with corneal opacity accompanied by extensive neovascularization, aniridia, severe ocular burns, Stevens-Johnson syndrome, and severe dry eye syndrome.
Exclusion criteria
Exclusion criteria: 1.Absolute glaucoma. 2.End-stage optic nerve and retinal diseases. 3.Amblyopia due to form deprivation. 4.Severe systemic diseases or contraindications to surgery. 5.Pregnant or breastfeeding women. 6.Patients with unstable mental status or a history of psychiatric disorders who are unable to comply with the study protocol.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| KPro retention time;Best Corrected Visual Acuity;Postoperative complications; | — |
Secondary
| Measure | Time frame |
|---|---|
| Quality of Life Score;Surgical Cycle; | — |
Countries
China
Contacts
Public ContactLiqiang Wang
Chinses PLA General Hospital
Outcome results
None listed