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Effect of sub-anesthesia dose of esketamine on oculocardiac reflex in pediatric strabismus surgery

Effect of sub-anesthesia dose of esketamine on oculocardiac reflex in pediatric strabismus surgery

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500096885
Enrollment
Unknown
Registered
2025-02-08
Start date
2025-02-10
Completion date
Unknown
Last updated
2025-02-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pediatric strabismus

Interventions

Control group 1:Intravenous anaesthesia: Equivalent saline
Intervention group 1:Intravenous anesthesia: 0.2 mg/kg esketamine for anesthesia induction
Control group 2:Sevoflurane inhalation anesthesia: equal amount saline
Intervention group 2:Sevoflurane inhalation anesthesia: 0.2 mg/kg of esketamine for anesthesia induction

Sponsors

Beijing Tongren Hospital Affiliated to Capital Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
2 Years to 12 Years

Inclusion criteria

Inclusion criteria: 1. Elective strabismus correction 2. ASA Class I-II 3. Age 2-12 years old 4. Anesthesia: general anesthesia with laryngeal mask 5. Consent to this study: Signed informed consent

Exclusion criteria

Exclusion criteria: 1. Have a history of receiving antiepileptic drugs or taking other medications known to affect the ECG 2. Presence of developmental or mental retardation 3. Presence of allergy to general anesthetic drugs

Design outcomes

Primary

MeasureTime frame
Incidence of oculocardiac reflex.;

Secondary

MeasureTime frame
Incidence of severe OCR;Number of atropine uses;Number of intraoperative hypoxic times;Number of postoperative nausea and vomiting;Number of postoperative agitations;

Countries

China

Contacts

Public ContactGuyan Wang

Beijing Tongren Hospital, Capital Medical University

guyanwang2006@163.com+86 139 1098 5139

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026