schizophrenia
Conditions
Interventions
Behavioral and Psychological Symptoms in Dementia:NA
Dementia without Behavioral and Psychological Symptoms:NA
Sponsors
Renmin Hospital of Wuhan University
Eligibility
Sex/Gender
All
Age
60 Years to 80 Years
Inclusion criteria
Inclusion criteria: (1) Voluntary signing of informed consent. (2) Commitment to comply with the study procedures and cooperate with the implementation of the entire research process. (3) Age between 60 and 80 years; (4) BPSD: Patients with severe neurocognitive impairment diagnosed according to DSM-5 criteria; dementia without behavior and psychological symptoms: Patients with mild neurocognitive impairment diagnosed according to DSM-5 criteria; (5) No recent otorhinolaryngological diseases and no medications that may affect olfactory function.
Exclusion criteria
Exclusion criteria: (1) Recent occurrence of cerebral parenchymal diseases such as cerebral hemorrhage or other serious physical diseases; (2) Disagree to participate in this study; (3) Unable to cooperate with the completion of the research project or be highly aggressive; (4) History of alcohol or drug abuse or psychoactive substance dependence; (5) History of nasal trauma or surgery, including surgeries such as nasal polyps and sinusitis; recent use of drugs that affect olfactory function.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Functional Near - Infrared Spectroscopy; | — |
Secondary
| Measure | Time frame |
|---|---|
| Self- Rating Scale of Sleep;Activity of Daily Living;Mini-mental State Examination;Generalized Anxiexy Disorde-7;The Brief Psychiatric Rating Scale;Patient Health Questionnaire-9;Montreal Cognitive Assessment;Niacin skin flushing response;Video of facial emotion changes; | — |
Countries
China
Contacts
Public ContactHuiling Wang
Renmin Hospital of Wuhan University
Outcome results
None listed