painless gastrointestinal endoscopy
Conditions
Interventions
Oliceridine+propofol:Oliceridine+propofol
fentanil+propofol:fentanil+propofol
Sponsors
Changshu NO.2 people's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1) Patients with an ASA classification of I to II; 2) Patients aged 18 to 65 years; 3) Patients scheduled for gastrointestinal endoscopy; 4) Body mass index (BMI) between 18.5 kg/m² and 30 kg/m²; 5) Patients who are able to understand and voluntarily sign the informed consent form, willing to comply with and are expected to complete the study requirements.
Exclusion criteria
Exclusion criteria: 1) Patients with insufficient fasting time (fasting < 6h, drinking < 2h) or gastrointestinal obstruction with gastric content retention; 2) Patients with mental disorders, intellectual disabilities, or hearing impairments; 3) Patients with alcohol abuse or a history of long-term use of sedative drugs; 4) Patients with acute respiratory infections or in the midst of an asthma attack; 5) Female patients who are pregnant or breastfeeding; 6) Patients with severe liver or kidney dysfunction or other serious complications.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of SpO2 < 95% or respiratory rate < 10 breaths/min; | — |
Secondary
| Measure | Time frame |
|---|---|
| Degree and incidence of respiratory depression;Total propofol dosage;incidence of hypotension;incidence of injection pain;success rate of inhibiting the gastric endoscopy insertion response;Endoscopy time;Wake time;Atropine and ephedrine dosage; | — |
Countries
China
Contacts
Public ContactHuang Ye
Changshu NO.2 people's Hospital
Outcome results
None listed