Application of Remimazolam besylate for injection in the induction of general anesthesia in lower limb surgery in elderly patients with hypertension

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2500096868

Enrollment

Unknown

Registered

2025-02-08

Start date

2025-02-10

Completion date

Unknown

Last updated

2025-02-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Orthopedic surgery

Interventions

Experimental group:Rimazolen 0.3mg/Kg iv

Control group:Etomidate 0.3mg/Kg iv

Eligibility

Sex/Gender

All

Age

60 Years to 80 Years

Inclusion criteria

Inclusion criteria: (1) Age 60-80 years old; (2) ASA grade II-III, cardiac function NYHA grade I-III; (3)BMI:18.5-29.9kg/m^2; (4) Lower limb surgery with hypertension; (5) Informed consent of patients and their families.

Exclusion criteria

Exclusion criteria: (1) Allergic to relevant drugs; (2) Preoperative hypertension was not properly controlled; (3) Preoperative presence of mental illness; (4) Severe heart and lung function, liver and kidney dysfunction; (5) Patient or family member refuses.

Design outcomes

Primary

Measure	Time frame
Mean arterial pressure (MAP);Heart rate (HR);Eye opening time;Extubation time;Duration of stay in the operating room after surgery;Wake Riker Sedation-Agitation Scale (RSAS) score;	—

Secondary

Measure	Time frame
Muscle tremors;Hypothermia;Postoperative cognitive dysfunction;	—

Countries

China

Contacts

Public ContactFang Qizhi

Xuyong County People's Hospital

875746150@qq.com+86 183 0831 0708

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026