Intracranial aneurysms
Conditions
Interventions
Control group:0.9% normal saline 10mL was injected through the endotracheal tube for drug injection
Experimental Group:1% lidocaine 10ml was injected through the endotracheal tube for drug injection
Sponsors
Huadong Hospital affiliated to Fudan University
Eligibility
Sex/Gender
All
Age
18 Years to 90 Years
Inclusion criteria
Inclusion criteria: 1. Patients with intracranial aneurysms undergoing interventional surgery under general anesthesia with endotracheal intubation; 2. ASA grade I-II; 3. Age >=18 years old; 4. Single lumen common endotracheal tube was placed; 5. Mallampatti grade I-III; 6. BMI 18-28 kg/m^2.
Exclusion criteria
Exclusion criteria: 1. Difficult intubation is expected or no extubation is expected after operation 2. preoperative communication disorders 3. Chronic cough 4. ACEI or antitussive drugs 5. History of allergy to amide local anesthetics 6. severe liver and kidney dysfunction/cardiovascular disease/nervous system disease 7. History of asthma or airway hypersensitivity 8. Recent respiratory infection/cold 9. High risk of reflux aspiration (pregnancy/obesity/gastrointestinal obstruction/emergency satiety/esophageal obstruction/esophagotracheal fistula/high intracranial pressure/nausea and vomiting/cardia relaxation/critical condition, etc.).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of bucking at extubation; | — |
Secondary
| Measure | Time frame |
|---|---|
| Vital signs;Agitation score before extubation;Sore throat score, cough score and hoarseness score ; | — |
Countries
China
Contacts
Public ContactGu Weidong
Huadong Hospital affiliated to Fudan University
Outcome results
None listed