Lung cancer
Conditions
Interventions
Observation group:None
Sponsors
Shandong First Medical University and Shandong Academy of Medical Sciences (Shandong Cancer Hospital &Institute)
Eligibility
Sex/Gender
Female
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1.>=18 years (no upper age limit); 2. Pathologically or cytologically confirmed NSCLC; 3. Stages I-II in the TNM stage of AJCC (8th edition) confirmed by clinicopathological stage; 4. Patients must be considered medically inoperable or refuse surgery; 5. ECOG PS 0-2; 6. For women of childbearing potential, a negative pregnancy test within 2 weeks prior to SBRT treatment; 7. Patient agrees and has the ability to follow the planned study visits, provide pre-treatment tissue specimens, blood specimens pre-treatment, 1 month post-treatment and follow-up, and cooperate with other study steps; 8. Patients must provide clear informed consent prior to study entry; 9. Use of adequate contraception during and for 6 weeks after treatment.
Exclusion criteria
Exclusion criteria: 1.Previous history of malignant tumor, and not cured; 2.There are contraindications to SBRT; 3.Other researchers consider it inappropriate to enroll.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| RECIST1.1 imaging response;ctDNA positivity rate at different time points; | — |
Secondary
| Measure | Time frame |
|---|---|
| Progression-Free Survival, PFS ; | — |
Countries
China
Contacts
Public ContactLigang Xing
Shandong First Medical University and Shandong Academy of Medical Sciences (Shandong Cancer Hospital &Institute)
Outcome results
None listed