bladder tumor
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.Meets the surgical indications for transurethral resection of bladder tumors; 2.Male patients aged 45-80 years; 3.ASA Grading 1-3; 4.body mass index (BMI) of 18-30 kg/m2; 5.There are no contraindications to anesthesia and pudendal nerve block;
Exclusion criteria
Exclusion criteria: 1.Patients with serious diseases of heart, brain, liver and kidney; 2.Those who refuse to operate pudendal nerve block or those who are unable to cooperate with mental illness; 3.Those who are allergic to the test drug; 4.Patients with coagulation abnormalities; 5.Patients with a history of dependence on sedative and analgesic drugs; 6.Patients with a history of long-term preoperative indwelling urinary catheter; 7.Lower urinary tract infection or obstruction, bladder irritation and other related symptoms;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The incidence of moderate to severe CRBD within 1 hour after surgery, including specific symptoms such as urinary intention, pain, and suffocation (immediately after extubation, 30 minutes, 1 hour); | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence of moderate and severe CTBD after surgery (2 hours, 4 hours, 6 hours);Incidence of delirium 6 hours postoperatively;VAS scores immediately after extubation and at 2h, 4h, and 6h after extubation;Ramsay sedation score immediately after extubation and at 2h, 4h, and 6h after extubation;Postoperative 24h QOR15 score;Intraoperative opioid use;Intraoperative atropine use;Time spent in the PACU;Blood pressure and heart rate upon entry into the operating room;Blood pressure and heart rate as the cystoscope enters the urethra;Blood pressure and heart rate at the beginning of resection;Blood pressure and heart rate at extubation;Blood pressure and heart rate at 30 min after extubation;Incidence of postoperative nausea and vomiting;Incidence of postoperative hypersedation;Incidence of postoperative respiratory depression;Time to first postoperative flatgas;The time of the first postoperative ambulation;Time to first postoperative bowel movement;Number of days in hospital;Patient satisfaction; | — |
Countries
China
Contacts
The Department of Anesthesiology, Affiliated Hospital of Xuzhou Medical University