None
Conditions
Interventions
S group:sugammadex
N group:neostigmine
Sponsors
Womens' Hospital, School of Medicine, Zhejiang University
Eligibility
Sex/Gender
Female
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: The inclusion criteria were the American Society of Anesthesiologists (ASA) physical status I-III, aged 18–60 years and BMI of 18-30 kg/m^2 undergoing elective laparoscopic gynecological surgery.
Exclusion criteria
Exclusion criteria: 1. patients who present with underlying pro-emetogenic diseases. 2. Patients with already using antiemetic or opioid drugs within 48h before surgery. 3. Patients with a history of neuromuscular diseases 4. Patients with preoperative history of hypersensitivity or contraindications to any drugs used in the protocol 5. patients who received gynecological laparoscopic surgery but converted to open surgery 6. Surgery time exceeds 3 hours or bleeding volume exceeds 500ml
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| the occurrence of PONV within 24h postoperatively; | — |
Secondary
| Measure | Time frame |
|---|---|
| severity of PONV;need for rescue antiemetic;need for rescue analgesia therapy;time to first flatus; | — |
Countries
China
Contacts
Public ContactXiaowei Qian
Womens' Hospital, School of Medicine, Zhejiang University
Outcome results
None listed