Gastric adenocarcinoma
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: (1) Gastric adenocarcinoma confirmed by gastroscopy biopsy (including papillary adenocarcinoma, tubular adenocarcinoma, mucinous adenocarcinoma and signet ring cell carcinoma according to WHO classification); (2) Poorly differentiated; (3) The clinical stage was T2-4N-/+M0; (4) Patients received neoadjuvant chemotherapy before surgery; (5) The number of neoadjuvant chemotherapy cycles >=2; (6) Patients underwent radical gastrectomy (R0 resection) after neoadjuvant chemotherapy; (7) The age of patients ranged from 18 to 80 years old. (8) Complete clinicopathological data.
Exclusion criteria
Exclusion criteria: (1) Patients received radiotherapy, targeted therapy, and immunotherapy before surgery; (2) Patients diagnosed with other malignant tumors at the same time or with a history of other malignant tumors; (3) The patient was diagnosed with gastric stump cancer; (4) The patient had severe abnormalities of lung, heart, liver and kidney function. (5) Patients with esophageal or gastrointestinal perforation during chemotherapy; (6) Patients with M1 detected during operation; (7) Patients with M1 confirmed by postoperative pathology; (8) Missing clinical data.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Gender;Age;Baseline body mass index;Tumor size;Clinical T staging;Preoperative chemotherapy;Preoperative chemotherapy cycles;Gross classification of tumors;Lauren classification of tumors;Location of the tumor;Histologic type of tumor; | — |
Countries
China
Contacts
West China Hospital, Sichuan University