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Study on the plasticity modulation effect of transcranial ultrasound stimulation on human brain and its detection technique

Study on the plasticity modulation effect of transcranial ultrasound stimulation on human brain and its detection technique

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500096812
Enrollment
Unknown
Registered
2025-02-07
Start date
2025-02-20
Completion date
Unknown
Last updated
2025-02-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None

Interventions

Sham group:Sham controlled transcranial focused ultrasound intervention and testing.
Parameter combination 1:Transcranial focused ultrasound intervention and testing.
Parameter combination 2:Transcranial focused ultrasound intervention and testing.
Parameter combination 3:Transcranial focused ultrasound intervention and testing.
Parameter combination 4:Transcranial focused ultrasound intervention and testing.

Sponsors

Zhenjiang Mental Health Center
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 50 Years

Inclusion criteria

Inclusion criteria: 1) Age 18-50 years old; 2) Good intellectual development; 3) Junior high school education or above; 4) No cardiovascular and cerebrovascular diseases such as hypertension; 5) After review by the International Neuropsychiatric Interview Scale, no mood disorders or mental illnesses such as anxiety and depression; 6) Not pregnant or breastfeeding women; 7) No intracranial metal implants, cochlear implants, increased intracranial pressure, brain trauma, skull incompleteness, brain tumors; 8) No neurological diseases, epilepsy, Parkinson's disease, stroke and other brain diseases; 9) No serious physical diseases, history of heart disease, pacemakers or implanted drug pumps, etc.;

Exclusion criteria

Exclusion criteria: 1) People with somatic sensory disorders; 2) People with motor dysfunction; 3) People with visual dysfunction; 4) People with a history of epilepsy or a family history of epilepsy, and those who use anticonvulsant drugs.

Design outcomes

Primary

MeasureTime frame
Motor evoked potential,MEP;

Secondary

MeasureTime frame
Transcranial magnetic stimulation evoked potentials,TEP;Stop Signal Task Related EEG;Behavioral data related to stop-signal tasks;Transcranial focused ultrasound evoked electroencephalography;

Countries

China

Contacts

Public ContactHu Qiang

Zhenjiang Mental Health Center

huqiang0704@163.com+86 139 0362 3702

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026