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The effect of prolonged preoperative fasting on the incidence of postoperative complications in cardiac surgery: a prospective randomized controlled study

The effect of prolonged preoperative fasting on the incidence of postoperative complications in cardiac surgery: a prospective randomized controlled study

Status
Unknown
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500096798
Enrollment
Unknown
Registered
2025-02-06
Start date
2025-02-10
Completion date
Unknown
Last updated
2026-01-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative complications

Interventions

Prolonged fasting group:Eat between 12:00 - 14:00 the day before surgery, fast after 14:00, and abstain from drinking after 00:00
Normal fasting group:Eat between 18:00 - 20:00 the day before surgery, fast after 20:00, and abstain from drinking after 00:00

Sponsors

Department of Anesthesiology, The First Affiliated Hospital of Army Medical University, Chongqing, China
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: (1) Patients who undergo coronary artery bypass grafting and valve replacement surgery under cardiopulmonary bypass in the elective morning; (2) Patients who eat normally by mouth; (3) patients with ASA<=III.; (4) Surgery time<=8 hours.

Exclusion criteria

Exclusion criteria: 1. Patients undergoing emergency surgery; 2. Age 70 years old; 3. BMI= 35.0kg/m^2 ; 4. Those who fast for a limited time and those who cannot eat normally by mouth; 5. Congenital heart disease, surgery involving aorta and aortic arch, pulmonary valve repair/replacement, tumors; 6. Patients with co-infection, including endocarditis, acute myocardial infarction, cardiac output 20µmol/L); 10. Coagulation abnormalities or taking anticoagulant drugs, not following the guidelines for preoperative bridging (INR>2.0); 11. Enrollment in other clinical studies; 12. Refusal to sign the consent form.

Design outcomes

Primary

MeasureTime frame
The rate of major complications after surgery;

Secondary

MeasureTime frame
The rate of major complications within postoperative 30 days;Mortality rate, cardiac and/or coronary reoperation rate within 1 year after surgery;

Countries

China

Contacts

Public ContactJiaolin Ning

Department of Anesthesiology, The First Affiliated Hospital of Army Medical University, Chongqing, China

460439856@qq.com+86 158 0801 4085

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026