Transforaminal Lumbar Endoscopic Discectomy versus Coblation Nucleoplasty combined with Collagenase Chemonucleolysis for Lumbar Disc Herniation with Grade I Degenerative Spondylolisthesis

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2500096787

Enrollment

Unknown

Registered

2025-02-06

Start date

2025-02-15

Completion date

Unknown

Last updated

2025-02-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

lumbar disc herniation

Interventions

IELD group:interlaminar endoscopic lumbar discectomy

CN combined with CCNL group:coblation nucleoplasty and Collagenase chemonucleolysis

Eligibility

Sex/Gender

All

Age

18 Years to 80 Years

Inclusion criteria

Inclusion criteria: (1)18=5 or lower extremity VAS score >=5, full score of 10; (5) Intermittent claudication < 200m (6) Voluntarily participate in the study and sign the informed consent.

Exclusion criteria

Exclusion criteria: (1) Patients with spinal tumors or infections; (2) Patients with degenerative lumbar spondylolisthesis type II and above; (3) Infection of the puncture site, bleeding disease or abnormal coagulation function; (4) Can not understand VAS, ODI, QoR-15, MacNab excellent rate. (5) Lost visitors.

Design outcomes

Primary

Measure	Time frame
visual analogue scale;	—

Secondary

Measure	Time frame
Quality-of-recovery 15;Oswestry disability index;MacNab criteria;	—

Countries

China

Contacts

Public ContactLikui Wang

Department of Pain, the First Affiliated Hospital of Anhui Medical University

wlk9560@163.com+86 137 0569 0702

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026