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An Observational Study on the Increased Synthesis of Fetal Hemoglobin Induced by Roxadustat in Patients with Renal Anemia

An Observational Study on the Increased Synthesis of Fetal Hemoglobin Induced by Roxadustat in Patients with Renal Anemia

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500096786
Enrollment
Unknown
Registered
2025-02-06
Start date
2025-01-03
Completion date
Unknown
Last updated
2025-02-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic kidney disease

Interventions

Exposed Group:None
Control Group:None

Sponsors

Army Military Medical University Second Affiliated Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Patients who visited the study site for the first time and were clearly diagnosed with chronic renal failure combined with renal anemia; 2. Age greater than 18 years old; 3. Willing to participate in this study and sign the informed consent form

Exclusion criteria

Exclusion criteria: Individuals who have received treatment with Yisui Shengxue Granules,Hydroxyurea, Thalidomide,Decitabine, Azacitidine, Sirolimus, Butyrate salts, or Progestogens within the past 3 months prior to enrollment; Individuals with anemia caused by other reasons that has not been corrected; Individuals with Thrombocytopenia (PLT 450×10^9/L); Patients with severe cardiovascular or cerebrovascular diseases; Individuals who have recently experienced stress, such as extreme environmental temperatures (too low or too high), surgery, poisoning, fright, or high-altitude reactions; Pregnant or breastfeeding women, and women of childbearing age who are unwilling to use contraception; Patients currently participating in other clinical trials; Patients with organic heart disease, coronary artery insufficiency, significant Arrhythmias, pulse > 100/min, or severe hypertension; Patients with respiratory diseases such as Bronchiectasis, asthma, interstitial lung disease, chronic obstructive pulmonary disease (COPD), other types of respiratory insufficiency, or active pulmonary tuberculosis; Individuals with a history of professional athletic training.

Design outcomes

Primary

MeasureTime frame
At the end of 12 months, %HbF increased from baseline levels;

Secondary

MeasureTime frame
MCHbF(12w)-MCHbF(0d);

Countries

China

Contacts

Public ContactChen Li

Army Military Medical University Second Affiliated Hospital

chenli200401@tmmu.edu.cn+86 151 7893 6688

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026