Gastroesophageal reflux disease
Conditions
Interventions
PECC group:Endoscopic cardiac constriction
Sponsors
Henan Provincial People's Hospita,medical
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Age>=18 years old; 2. Those who have been diagnosed with GERD through symptoms and signs, 24-hour esophageal pH monitoring or gastroscopy; 3. Symptoms that have not been relieved significantly for more than 2 months after systematic internal medicine treatment or recurrence after remission; 4. Voluntarily participate in this study and sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Combined hiatal hernia with a length of >2cm; 2. Severe reflux esophagitis (Los Angeles grade C, D grade); 3. Patients with Barrett's esophagus or early-stage cancer confirmed by biopsy; 4. Those who have undergone surgical treatment such as gastric plication and have destroyed the normal physiological and anatomical structure; 5. Patients with severe dysphagia, esophageal motility, esophageal stricture, achalasia and other diseases; 6. Those with allergies or severe cardiopulmonary dysfunction who cannot receive endoscopic treatment or are unwilling to undergo endoscopic treatment; 7. Pregnant and lactating women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 24h esophageal pH monitoring;Symptom score;Esophageal pressure measurement results;Gastroscopy presentation (RE Los Angeles grading); | — |
Secondary
| Measure | Time frame |
|---|---|
| Use of PPIs before and after surgery;Surgical costs;Surgical time;Post-operative hospitalisation days;Postoperative adverse reaction;Relapse rate; | — |
Countries
China
Contacts
Public ContactDing hui
Henan Provincial People's Hospita,medical
Outcome results
None listed